A modeling-guided case study of disordered speech in minimally verbal children with autism spectrum disorder

KV Chenausky; A Brignell; AT Morgan; AC Norton; HB Tager-Flusberg; G Schlaug; FH Guenther

Journal article

A modeling-guided case study of disordered speech in minimally verbal children with autism spectrum disorder

KV Chenausky, A Brignell, AT Morgan, AC Norton, HB Tager-Flusberg, G Schlaug, FH Guenther

American Journal of Speech Language Pathology | Published : 2021

DOI: 10.1044/2021_AJSLP-20-00121

Abstract

Purpose: Understanding what limits speech development in minimally verbal (MV) children with autism spectrum disorder (ASD) is important for providing highly effective targeted therapies. This preliminary investigation explores the extent to which developmental speech deficits predicted by Directions Into Velocities of Articulators (DIVA), a computational model of speech production, exemplify real phenotypes. Method: Implementing a motor speech disorder in DIVA predicted that speech would become highly variable within and between tokens, while implementing a motor speech plus an auditory processing disorder predicted that DIVA’s speech would become highly centralized (schwa-like). Acoustic a..

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University of Melbourne Researchers

Angela Morgan Author

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Grants

Awarded by National Institute on Deafness and Other Communication Disorders

Funding Acknowledgements

This work was supported by P50 DC 13027 to H. T. F. (supporting H. T. F., G. S., A. C. N., and K. V. C.), P50 DC 18006 to H. T. F. (supporting H. T. F. and K. V. C.), the Nancy Lurie Marks Family Foundation and Autism Speaks (supporting G. S.), T32 DC 013017 to C. A. Moore (supporting K. V. C.), a Clinical Research Grant from the American Speech-Language-Hearing Foundation (supporting K. V. C.), K99 DC 017490 (to K. V. C.), an National Health and Medical Research Council (NHMRC) Practitioner Fellowship 1105008 (to A. M.), an NHMRC Centre of Research Excellence in Speech and Language Neurobiology 1116976 (to A. M.), and NHMRC Project Grant 1127144 (to A. M.).